i always fail to build bowtie2 index of full_chocophlan database because i haven’t enough memory, so can anyone offer a bowtie2 index of full_chocophlan database(full_chocophlan.v201901_v31) for me？
Can you explain why you’re trying to map against the full database? This is usually not the best procedure to pick (in part due to the sort of performance issues you note, and in part due to the potential for false positive hits).