HUMAnN

Topic	Replies	Views	Activity
MetaPhlAn 4 + HUMAnN 4 compatibility HUMAnN users - I’m making a quick pinned post about MetaPhlAn 4 + HUMAnN 4 compatibility since we’re seeing a lot of posts raising similar issues. We will follow up with more detailed information in the short term, and l…	23	2359	July 24, 2026
Announcing HUMAnN 4.0 (alpha) Dear HUMAnN users: HUMAnN 4.0 (alpha) has arrived! Many thanks for your patience—we know there have been a lot of users looking forward to this release for a long time. Since a lot is changing in this version, we’re tryi…	3	3717	February 2, 2026
HUMAnN database download	27	2579	August 4, 2026
Joint taxonomic profile with metaphlan 4 and humann 4	0	30	July 20, 2026
--nucleotide-identity-threshold does not change run config or results (humann v3.8)	0	14	July 17, 2026
Help with using HUMAnN4	0	33	July 6, 2026
Pathcoverage vs Pathabundance for filtering - some numbers where I don't understand how they can happen	0	24	June 30, 2026
HUMAnN 4 database downloads inaccessible due to Globus (data.globus.org) domain blocking	4	152	June 23, 2026
HUMAnN v4.0.0.alpha.1 Raw Counts	3	91	June 22, 2026
How to get count data (not RPK)?	2	138	June 22, 2026
HUMAnN4 Support for MetaPhlAn vJan25 Database	2	223	June 4, 2026
Custom MetaPhlAn subspecies taxonomy + corresponding HUMAnN ChocoPhlAn pangenome design	2	42	May 28, 2026
Everything is unclassified	4	70	May 28, 2026
HUMAnN v4 alpha: clarification on 0.5x coverage threshold and low-abundance taxa filtering	1	53	May 22, 2026
Humann4 conda install from release note	1	91	May 14, 2026
What’s is needed to build a custom HUMANN database?	7	1143	April 29, 2026
Unable to download Databases	10	120	April 23, 2026
Metaphlan 4 using with Humann3.9	5	624	April 21, 2026
Can't download Uniref database	0	23	April 20, 2026
Humann_unpack_pathways command	5	273	April 15, 2026
Matching tools and database versions	8	209	April 9, 2026
Tutorial not up to date and unable to run successfully	0	58	April 5, 2026
No full uniref90 db in humann4	2	184	March 30, 2026
Humann 3.9 conda install will not work. Please update your version of MetaPhlAn?	6	586	March 9, 2026
Humann3 hanging during run, no error messages but no changes to output, log or temp files	21	1140	March 9, 2026
Very low mapping rate of Hummann v4alpha	3	160	March 6, 2026
Latest Stable version of HUMANn and MetaPhlAN for maximum downstream compatibility	0	221	March 3, 2026
Unable to download ChocoPhlAn and UniRef databases (connection error)	2	89	March 2, 2026
Best publication to referenec when citing humann4	0	45	February 26, 2026
Analyzing single end and paired end reads together?	0	27	February 20, 2026

MetaPhlAn 4 + HUMAnN 4 compatibility

HUMAnN users - I’m making a quick pinned post about MetaPhlAn 4 + HUMAnN 4 compatibility since we’re seeing a lot of posts raising similar issues. We will follow up with more detailed information in the short term, and l…

23

2359

July 24, 2026

Announcing HUMAnN 4.0 (alpha)

Dear HUMAnN users: HUMAnN 4.0 (alpha) has arrived! Many thanks for your patience—we know there have been a lot of users looking forward to this release for a long time. Since a lot is changing in this version, we’re tryi…