Unable to download Databases

Microbial community profiling HUMAnN
1

I’m unable to download any of the databases using the commands provided in the tutorial. Has anyone encountered this issue or know what might be going wrong?

humann_databases --download chocophlan DEMO humann_dbs
humann_databases --download uniref DEMO_diamond humann_dbs

Even when trying it with the wget command it does not work. Is there a way to fix this?

2

I am also having this problem. I think the server may be offline for maintenance. It was working last week.

1 Like
3

It seems to be working now

4

Hello @ThibaultWilmsen and @suz ,

Apologies for the inconvenience earlier. The database downloads should now be back online. The interruption was due to a temporary server outage, which has been resolved.

Please try again, and let us know if you continue to experience any issues.

Rgards,
Sagun

5

Hi, I’m unable to download any databases, both when using humann_database --download … and wget. Wondering if there has been another server outage or if the issue is on my end?

thanks

6

Hi @nikeaulrich ,
Can you give it one more try now please? I have remounted the database after the server outage.

Regards,
Sagun

7

Hi @sagunmaharjann thanks! I just tried and it still isn’t downloading for some reason.

humann_databases --download utility_mapping full /humann_dbs/

I get this: Download URL: http://huttenhower.sph.harvard.edu/humann_data/full_mapping_v4_alpha.tar.gz

but nothing downloads

Thanks, Nikea

8

using wget, I get this:

--2026-04-23 13:54:07--  http://huttenhower.sph.harvard.edu/humann_data/full_mapping_v4_alpha.tar.gz

Resolving huttenhower.sph.harvard.edu (huttenhower.sph.harvard.edu)... 199.94.60.28

Connecting to huttenhower.sph.harvard.edu (huttenhower.sph.harvard.edu)|199.94.60.28|:80... connected.

HTTP request sent, awaiting response... 302 Found

Location: https://huttenhower.sph.harvard.edu/humann_data/full_mapping_v4_alpha.tar.gz [following]

--2026-04-23 13:54:07--  https://huttenhower.sph.harvard.edu/humann_data/full_mapping_v4_alpha.tar.gz

Connecting to huttenhower.sph.harvard.edu (huttenhower.sph.harvard.edu)|199.94.60.28|:443... connected.

Still nothing downloads sadly

9

Hi @nikeaulrich ,
This issue might be on your end, a few other users have confirmed that downloads are working now. I just double checked on my end as well and looks fine.

wget http://huttenhower.sph.harvard.edu/humann_data/full_mapping_v4_alpha.tar.gz

Regards,
Sagun

10

Thank you so much for confirming. I appreciate it. I’ll keep troubleshooting.

11

I’m not sure what is tripping up wget but I am able to download using curl -L if anyone else runs into the issues I was. Thanks again!