Hi everyone, I have a question about the MetaPhlAn database extension.
I’m analysing gut metagenomes, in which a lot of reads came back as “unclassified.” With assembly, I have obtained the unclassified MAGs from my samples. I was thinking of adding the markers from these MAGs to the MetaPhlAn database to see if I can get more reads mapped with an extended database.
Has anyone done this with the recent database versions? I’m looking for the best way to do this with the latest version of MetaPhlAn, as I know this has been a tricky issue in the past.
Any possible solution would help a lot.
Thank you