Can I possibly use mpa_v30 on an older version of metaphlan?

[Cheng_Li]

Hello everyone,

I would like to seek some help on using an older version of metaphlan (version 1) to run the database mpa_v30.
I don’t have much permit to install new packages on our server so I was trying to run an older version of metaphlan to resolve the phylogeny of my metagenomic data.

I was wondering if I can, and how I can apply the newest version of db v30 to the older version of metaphlan.

many thanks,
Cheng

[Marco_Severgnini]

Hello @Cheng_Li , I don’t know if you resolved your problem. Anyway, I think that latest versions of the databases are not backward compatible, as repoted here:

Most recent databases for Humann2

Hi all, I’m still running the “old” HUMAnN2 pipeline, but I suspect that reference databases are not up to date anymore. I’m wondering if and where I could find the updated chocophlan, Uniref and metaphlan databases (i.e.: the same used for HUMANn3, if compatible) to be used in HUMANn2. Thank you very much in advance Marco

Hope this helps.
Marco

[Cheng_Li]

Thanks Marco. A staff from my facility helped me to compile the environment on our server. Now I am able to run Metaphlan and Humann3 now.