Use of Lefse-LDA Analysis

I am writing to you to ask about the following:

Is it possible to adjust our LDA analysis using the module by important demographic parameters such as age and gender? How can I have an adjusted LDA score adjusted by age and gender or even other confounding factors?

Sincerely grateful if you could provide any insight into my question or point me in the right direction.

Hi Yik,

Can you take a look at one of our other bioBakery tools i.e. MaAsLin2?

User manual: