Sensitivity of MetaPhlAn Metatranscriptomics

How suitable is MetaPhlAn for metatranscriptomics analysis? The marker genes of each species are derived from analysis of the uniqueness of genomic sequences. If a particular species has five markers genes but only two of them are transcribed, will it report that species as being detected? More generally, has MetaPhlAn been evaluated using a commercially-available mock community? What is the algorithm’s sensitivity? I am wondering about the false negative rate.