MetaPhlAn 4 + HUMAnN 4 compatibility

[fconstancias]

Hello Biobakers,

I am wondering if you have some updates on this?

Many thanks!

@fconstancias

Same with a fresh installation here:
mpa_vJan21_CHOCOPhlAnSGB_202103.tsv and vOct22_SGB_mapping.tsv.

Is it really compatible with MetaPhlAn v4.1.1 + mpa_vOct22_CHOCOPhlAnSGB_202403?

When installing HUMAnN following the details here, MetaPhlAn v4.2.4 is installed.

humann --version
humann v4.0.0.alpha.1

metaphlan --version
MetaPhlAn version 4.2.4 (21 Oct 2025)

Some clarification would be super helpful !