Matching/linking profiled species using MetaPhlAn3 (v3.0.1) to MetaPhlAn (4.2.4),database: mpa_vJan25_CHOCOPhlAnSGB_202503

Hi there,

I am working with a couple of microbes that were initially profiled using Metaphlan3 (v3.0.1). I am currently profiling my samples to gauge the abundance ( and later do strainphlan analysis) of those exact same microbes. However, I am using Metaphlan4 (v4.2.4) with the mpa_vJan25_CHOCOPhlAnSGB_202503 database installed. It seems some of those microbes are absent in the Metaphlan4 database I am using. Some of these apparently missing microbes include - Eubacterium_sp_CAG_38, Eubacterium_sp_CAG_251, Eubacterium_sp_CAG_180, Oscillibacter_sp_CAG_241 and Oscillibacter_sp_57_20.

How can I determine the corresponding names of these microbes in the metaphlan4 database, especially if these microbes have been reclassified/renamed? I’d be grateful if you pointed me to how I can resolve this issue.

Thanks,