I apologize if this is a duplicate post; I went through the forum to see if others were having similar problems and couldn’t find anything on it.
I have run HUMANn3 on my mouse microbial samples and found ~10^6 gene families (an amazing improvement from HUMANn2). These however only map to ~12 EC IDs when using the mapping file provided. When I run the UniRef90 IDs in UniProt, their database is able to map to many more EC IDs.
Does anyone have any insight on why there is such a huge discrepancy? Is there a way I can get an updated mapping file (hopefully short of making my own, I’m still a rookie bioinformatician but I can certainly give it a go!).
Thank you so much, this forum has been incredibly helpful.