Interpretation of effect sizes

Downstream analysis and statistics MaAsLin
1

Hello again,

Is there any standardisation of actual effect sizes in Maaslin, or do I need to take in to account the relative abundance of the various species when I am interpreting these? I am using relative abundance data and selecting “normalisation = CLR” and “transformation = none”.

I understand that if I opt for “standardisation = TRUE” , the metadata scales are standardised using Z-scores, however I couldn’t see anything about the relative abundance data.

Many thanks,
Katherine

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2

Hi there,

You need to keep in mind the units that you are measuring against which in this case would be CLR normalized abundances.

To get a better idea on interpretation of effect sizes check out this forum post here:

Cheers,
Jacob Nearing

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