Interpretation of effect sizes

Hello again,

Is there any standardisation of actual effect sizes in Maaslin, or do I need to take in to account the relative abundance of the various species when I am interpreting these? I am using relative abundance data and selecting “normalisation = CLR” and “transformation = none”.

I understand that if I opt for “standardisation = TRUE” , the metadata scales are standardised using Z-scores, however I couldn’t see anything about the relative abundance data.

Many thanks,

Hi there,

You need to keep in mind the units that you are measuring against which in this case would be CLR normalized abundances.

To get a better idea on interpretation of effect sizes check out this forum post here:

Jacob Nearing