Coefficient value greater than 1


I am having results from running Maaslin2 and one feature reports a coefficient of 1.26. Is this normal? It seems weird.

Thank you,

Hi Giorgio - one quick way to verify this would be to look at the corresponding scatter/box plot and see if this effect size translates to the strong association your are seeing.

Hi Himel,

Thank you for your answer. So you are telling that it is possible to have a value greater/smaller than +/- 1 and it is only a matter of verifying the strength. Should maximum strength max out at |1| ?

Hi @Giorgio_Casaburi - if you standardize (z-score) the metadata (which is only done for continuous variables when prompted), you will indeed get standardized beta coefficients ranging between -1 and 1. Otherwise, you can get coefficients greater than 1.

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Sir @himel.mallick , I also have faced the same thing as I run with everything default. Can you please tell me what is the minimum co-efficient I should consider to call the features as differentially abundant? Or, should I consider all the features in the significant_results.tsv file?