Hi, Im trying to understand what happens to a read gets mapped to more than one database entry in the translated search. In the HUMAnN2 paper I found this: “If a read has two or more high-quality alignments to distinct database sequences, the read’s single count is divided across the corresponding sequences in proportion to squared alignment identity”.
Can you please clarify what this means?
Also, as far as I can understand, this was not changed in HuMAnN3 - could you please varify this?
Thanks in advance,