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Does Maaslin2 supports longitudinal data analysis?

Hi developer,

May I know does MaAsLin2 supports longitudinal microbiome data analysis?
I have attached my demo meta data. I have 200 samples(treatment: 100 case vs 100 control), belongs to 40 subjects, while each subject has 5 timepoints. I want to test the effect of treatment, time.

Much appreciated!
demo.csv (8.5 KB)

Hi @Chloe - it does. You need to specify subjects as random effects (to account for repeated measures) and treatment, time as fixed effects.

All the best,
Himel

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