# Run Humann on uniref90\_201901 database

**URL:** <https://forum.biobakery.org/t/run-humann-on-uniref90-201901-database/7909>\
**Category:** HUMAnN\
**Created:** [March 11, 2025, 4:30pm UTC](https://forum.biobakery.org/t/run-humann-on-uniref90-201901-database/7909 "2025-03-11T16:30:55Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![blan](https://avatars.discourse-cdn.com/v4/letter/b/77aa72/32.png) [@blan](https://forum.biobakery.org/u/blan)\
**Post date:** [March 11, 2025, 4:30pm UTC](https://forum.biobakery.org/t/run-humann-on-uniref90-201901-database/7909/1 "2025-03-11T16:30:55Z")

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Hi,  
I’m using humann version 3.9. I want to run it on a series of files where I have performed MetaPhlAn community profiling using MPA3 algorithm and database mpa\_v30\_CHOCOPhlAn\_201901.  
I want to perform the next step with Humann on Diamond’s uniref90\_201901 version. It seems that my installed Diamond database is a slightly different version: the file is named uniref90\_201901b\_full.dmnd, which leads me to believe I have uniref90\_201901_ **b** _ instead of uniref90\_201901.  
However, if I try to download this version with:  
`humann_databases --download uniref uniref90_201901 uniref90/`  
I get an error:  
`ERROR: Please select an available build.`  
Are uniref90\_201901 and uniref90\_201901b different databases? Is there a way to download uniref90\_201901 instead of uniref90\_201901b?

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**Author:** ![franzosa](https://yyz1.discourse-cdn.com/flex027/user_avatar/forum.biobakery.org/franzosa/32/3511_2.png) [@franzosa](https://forum.biobakery.org/u/franzosa)\
**Post date:** [April 11, 2025, 6:11pm UTC](https://forum.biobakery.org/t/run-humann-on-uniref90-201901-database/7909/2 "2025-04-11T18:11:37Z")

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I believe `uniref90_201901b` was a bug fix to the original HUMAnN 3 database (provided with the alpha) that was called `uniref90_201901`. So they are not the same, but the `b` version would be the correct one to use with HUMAnN 3.