# QUESTION: StrainPhlAn working with a genome?

**URL:** <https://forum.biobakery.org/t/question-strainphlan-working-with-a-genome/1534>\
**Category:** StrainPhlAn\
**Created:** [January 14, 2021, 11:00am UTC](https://forum.biobakery.org/t/question-strainphlan-working-with-a-genome/1534 "2021-01-14T11:00:23Z")\
**Posts on this page:** 1\
**Showing post:** 4

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**Author:** ![aitor.blancomiguez](https://yyz1.discourse-cdn.com/flex027/user_avatar/forum.biobakery.org/aitor.blancomiguez/32/86_2.png) [@aitor.blancomiguez](https://forum.biobakery.org/u/aitor.blancomiguez)\
**Post date:** [January 18, 2021, 10:44am UTC](https://forum.biobakery.org/t/question-strainphlan-working-with-a-genome/1534/4 "2021-01-18T10:44:02Z")

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Hi Lorenzo,  
The latest CHOCOPhlAn version is 201901, so you are actually using the latest one. That a species has no markers in the MetaPhlAn database could be due to different factors, like we were not able to find, at least, 10 species-unique marker, or that at the time the database was created, no annotated genome of those species was present in the UniProt Proteomes portal.  
I will point @fbeghini here, he was the person in charge of building this database and probably he can help you better than me through this process. In the meanwhile, you can take a look on this post opened recently in the MetaPhlAn subforum: [How to create marker sequences from a genome to add to metaphlan database?](https://forum.biobakery.org/t/how-to-create-marker-sequences-from-a-genome-to-add-to-metaphlan-database/1160)  
Best,  
Aitor

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