# Pathways in Result But Not in MetaCyc Database **URL:** \ **Category:** HUMAnN\ **Created:** [June 9, 2021, 8:00am UTC](https://forum.biobakery.org/t/pathways-in-result-but-not-in-metacyc-database/2225 "2021-06-09T08:00:09Z")\ **Posts on this page:** 3\ **Page:** 1
**Author:** ![Dario](https://avatars.discourse-cdn.com/v4/letter/d/bc79bd/32.png) [@Dario](https://forum.biobakery.org/u/Dario)\ **Post date:** [June 9, 2021, 8:00am UTC](https://forum.biobakery.org/t/pathways-in-result-but-not-in-metacyc-database/2225/1 "2021-06-09T08:00:09Z")
Looking through the results, almost all pathways have names. For example PWY-6163 is chorismate biosynthesis from 3-dehydroquinate 0.999 But, when I look at PWY-4242, it is blank. ```auto PWY-4242 0.9999527979 PWY-4242|g __Fusobacterium.s__ Fusobacterium_nucleatum 0.0384455671 PWY-4242|g __Fusobacterium.s__ Fusobacterium_periodonticum 0.3948018469 PWY-4242|g __Porphyromonas.s__ Porphyromonas_endodontalis 0.1519649698 PWY-4242|unclassified 0.0002206948 PWY-4242|g __Fusobacterium.s__ Fusobacterium_sp_oral_taxon_370 0.0302844385 PWY-4242|g __Campylobacter.s__ Campylobacter_rectus 0.0572872704 PWY-4242|g __Aggregatibacter.s__ Aggregatibacter_segnis 0.1268270103 PWY-4242|g __Dialister.s__ Dialister_invisus 0.1279188885 ``` Checking MetaCyc website, it is not found unlike PWY-6163. Perhaps it has been removed for some special reason. How can I interpret this situation? ![image](https://canada1.discourse-cdn.com/flex027/uploads/biobakery/original/1X/4d7baa3dcdf31c3df2150cd0aa5bf430f40f7ad0.png) ---
**Author:** ![franzosa](https://yyz1.discourse-cdn.com/flex027/user_avatar/forum.biobakery.org/franzosa/32/3511_2.png) [@franzosa](https://forum.biobakery.org/u/franzosa)\ **Post date:** [June 9, 2021, 7:38pm UTC](https://forum.biobakery.org/t/pathways-in-result-but-not-in-metacyc-database/2225/2 "2021-06-09T19:38:50Z")
The newest HUMAnN (3.0.0) provided a big update to the MetaCyc pathway definitions; if you upgrade you will probably find them in better agreement with the modern MetaCyc website. Note that you don’t have to reprofile your samples from raw reads to update the pathways - you can rerun HUMAnN 3 starting from your genefamilies file as an input. ---
**Author:** ![Dario](https://avatars.discourse-cdn.com/v4/letter/d/bc79bd/32.png) [@Dario](https://forum.biobakery.org/u/Dario)\ **Post date:** [June 9, 2021, 11:00pm UTC](https://forum.biobakery.org/t/pathways-in-result-but-not-in-metacyc-database/2225/3 "2021-06-09T23:00:12Z")
I should have mentioned that I used HUMAnN version 3.0.0 and this seemingly deprecated pathway was in the result.