# MetaPhlAn2 and MetaPhlAn3 shows different ouput

**URL:** <https://forum.biobakery.org/t/metaphlan2-and-metaphlan3-shows-different-ouput/3563>\
**Category:** MetaPhlAn\
**Created:** [May 10, 2022, 7:29pm UTC](https://forum.biobakery.org/t/metaphlan2-and-metaphlan3-shows-different-ouput/3563 "2022-05-10T19:29:13Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![shreya](https://avatars.discourse-cdn.com/v4/letter/s/ecccb3/32.png) [@shreya](https://forum.biobakery.org/u/shreya)\
**Post date:** [May 10, 2022, 7:29pm UTC](https://forum.biobakery.org/t/metaphlan2-and-metaphlan3-shows-different-ouput/3563/1 "2022-05-10T19:29:13Z")

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Hi,  
I ran MetaPhlAn2 and MetaPhlAn3 together for the same sample.  
v2 shows more diverse microbial communities including Bacteria, Virus and Eukaryotes where as v3 show 100% Bacteria. Which seems unreliable database. Which one should be the accurate output?

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**Author:** ![aitor.blancomiguez](https://yyz1.discourse-cdn.com/flex027/user_avatar/forum.biobakery.org/aitor.blancomiguez/32/86_2.png) [@aitor.blancomiguez](https://forum.biobakery.org/u/aitor.blancomiguez)\
**Post date:** [December 19, 2022, 4:38pm UTC](https://forum.biobakery.org/t/metaphlan2-and-metaphlan3-shows-different-ouput/3563/2 "2022-12-19T16:38:12Z")

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Hi @shreya  
I would rely on the metaphlan 3 results since they were proved more accurate in latest evaluations [https://elifesciences.org/articles/65088](https://elifesciences.org/articles/65088)