Maaslin2 vs MMUPHin

Downstream analysis and statistics MaAsLin
3

Thank you Andrew for your clear reply.
One more question -
Under this thread Choosing analysis method for maaslin2 it’s mentioned :

  • Among the normalization approaches implemented in MaAsLin 2, TMM and CSS only work on counts and they also return normalized counts unlike TSS and CLR. Therefore, if your input is count, you can use the above two normalizations (i.e., TMM, CSS, or NONE (in case the data is already normalized)) without a further transformation (i.e. transform = 'NONE').

I understand from here that with counts it would be better to use TMM or CSS with no normalization? However, you suggest that TSS with LOG should be ok with 16S count data as well ?
Thank you for helping out!