# Lefse for Temporal comparitive analysis

**URL:** <https://forum.biobakery.org/t/lefse-for-temporal-comparitive-analysis/1931>\
**Category:** LEfSe\
**Created:** [April 14, 2021, 10:56am UTC](https://forum.biobakery.org/t/lefse-for-temporal-comparitive-analysis/1931 "2021-04-14T10:56:11Z")\
**Posts on this page:** 1\
**Showing post:** 2

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**Author:** ![mishort](https://yyz1.discourse-cdn.com/flex027/user_avatar/forum.biobakery.org/mishort/32/556_2.png) [@mishort](https://forum.biobakery.org/u/mishort)\
**Post date:** [May 14, 2021, 3:59pm UTC](https://forum.biobakery.org/t/lefse-for-temporal-comparitive-analysis/1931/2 "2021-05-14T15:59:43Z")

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Hello,  
Thanks for your question. A previous thread addresses this question I believe: [Longitudinal data in Lefse](https://forum.biobakery.org/t/longitudinal-data-in-lefse/1493)

Basically, LEfSe isn’t designed to accommodate different time points, but MaAsLin2 is suited for that kind of analysis. I hope that helps!  
Best,  
Meg

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