# HUMAnN4 Support for MetaPhlAn vJan25 Database

**URL:** <https://forum.biobakery.org/t/humann4-support-for-metaphlan-vjan25-database/8676>\
**Category:** HUMAnN\
**Created:** [December 12, 2025, 7:36am UTC](https://forum.biobakery.org/t/humann4-support-for-metaphlan-vjan25-database/8676 "2025-12-12T07:36:13Z")\
**Posts on this page:** 3\
**Page:** 1

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**Author:** ![Wan-YuLin](https://yyz1.discourse-cdn.com/flex027/user_avatar/forum.biobakery.org/wan-yulin/32/2744_2.png) [@Wan-YuLin](https://forum.biobakery.org/u/Wan-YuLin)\
**Post date:** [December 12, 2025, 7:36am UTC](https://forum.biobakery.org/t/humann4-support-for-metaphlan-vjan25-database/8676/1 "2025-12-12T07:36:13Z")

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Hi,

Many thanks for updating MetaPhlAn to v2.2, which now supports the latest vJan25 database.  
I noticed that HUMAnN v4.0.0-alpha currently supports only the vOct22 database.

Will the upcoming HUMAnN 4 release support the latest vJan25 database?

Thanks!

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**Author:** ![franzosa](https://yyz1.discourse-cdn.com/flex027/user_avatar/forum.biobakery.org/franzosa/32/3511_2.png) [@franzosa](https://forum.biobakery.org/u/franzosa)\
**Post date:** [January 9, 2026, 8:24pm UTC](https://forum.biobakery.org/t/humann4-support-for-metaphlan-vjan25-database/8676/2 "2026-01-09T20:24:33Z")

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Yes, hopefully soon! Jan25 is being tested and is the next major release HUMAnN 4 will support (skipping over Jun23).

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**Author:** ![Bjabbar](https://yyz1.discourse-cdn.com/flex027/user_avatar/forum.biobakery.org/bjabbar/32/3654_2.png) [@Bjabbar](https://forum.biobakery.org/u/Bjabbar)\
**Post date:** [June 4, 2026, 6:53pm UTC](https://forum.biobakery.org/t/humann4-support-for-metaphlan-vjan25-database/8676/3 "2026-06-04T18:53:46Z")

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That is great. Do you suggest waiting for the new release or going a few versions back? Any expected date for the big release?