# HUMANn 4 + MetaPhlAn 4

**URL:** <https://forum.biobakery.org/t/humann-4-metaphlan-4/8093>\
**Category:** HUMAnN\
**Created:** [May 30, 2025, 3:11pm UTC](https://forum.biobakery.org/t/humann-4-metaphlan-4/8093 "2025-05-30T15:11:28Z")\
**Posts on this page:** 1\
**Showing post:** 7

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**Author:** ![franzosa](https://yyz1.discourse-cdn.com/flex027/user_avatar/forum.biobakery.org/franzosa/32/3511_2.png) [@franzosa](https://forum.biobakery.org/u/franzosa)\
**Post date:** [June 30, 2025, 3:14pm UTC](https://forum.biobakery.org/t/humann-4-metaphlan-4/8093/7 "2025-06-30T15:14:29Z")

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I have replied to the new post you created here:

> [@Humann 4 cant work with metaphlan 4](https://forum.biobakery.org/t/humann-4-cant-work-with-metaphlan-4/8201/2):
>
> We will be adding support for MetaPhlAn 4.2 + the Jan25 SGBs in the next release of HUMAnN. Right now the HUMAnN 4 alpha does not yet support these latest versions. My recommendation would be to stick with running HUMAnN 4 with MetaPhlAn 4.1 + the Oct22 SGBs for now. If you’d like to also experiment with MetaPhlAn 4.2, you could do so in a separate conda environment. If you would like to use MetaPhlAn 4.2 output with HUMAnN, you could run MetaPhlAn outside of HUMAnN including the following flag…

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