# Downlodaing UniRef90 full database

**URL:** <https://forum.biobakery.org/t/downlodaing-uniref90-full-database/2464>\
**Category:** HUMAnN\
**Created:** [August 6, 2021, 2:56pm UTC](https://forum.biobakery.org/t/downlodaing-uniref90-full-database/2464 "2021-08-06T14:56:54Z")\
**Posts on this page:** 5\
**Page:** 1

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**Author:** ![Ivy](https://avatars.discourse-cdn.com/v4/letter/i/bc8723/32.png) [@Ivy](https://forum.biobakery.org/u/Ivy)\
**Post date:** [August 6, 2021, 2:56pm UTC](https://forum.biobakery.org/t/downlodaing-uniref90-full-database/2464/1 "2021-08-06T14:56:55Z")

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Could anyone help me with a dropbox or any other link to download UniRef90\_annotated\_v201901b\_full database? I am trying from [Index of /databases/HUMAnN](http://cmprod1.cibio.unitn.it/databases/HUMAnN/) but unable to do so. Previously, I downloaded uniref90\_annotated\_v201901.tar.gz through _humann\_databases --download uniref uniref90\_diamond $INSTALL\_LOCATION_ but facing version related issue. I am using humann v3.0.0.

Any help is much appreciated.

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**Author:** ![franzosa](https://yyz1.discourse-cdn.com/flex027/user_avatar/forum.biobakery.org/franzosa/32/3511_2.png) [@franzosa](https://forum.biobakery.org/u/franzosa)\
**Post date:** [August 6, 2021, 6:21pm UTC](https://forum.biobakery.org/t/downlodaing-uniref90-full-database/2464/2 "2021-08-06T18:21:03Z")

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Can you post the error message you are seeing? Using `humann_databases` is still the preferred way to fetch the databases (we don’t have them mirrored in Dropbox, unless someone else has done that unofficially).

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**Author:** ![Ivy](https://avatars.discourse-cdn.com/v4/letter/i/bc8723/32.png) [@Ivy](https://forum.biobakery.org/u/Ivy)\
**Post date:** [August 7, 2021, 11:17am UTC](https://forum.biobakery.org/t/downlodaing-uniref90-full-database/2464/3 "2021-08-07T11:17:06Z")

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Hi Eric, @franzosa I am using humann v3.0.0. I have downloaded Chocophlan and Uniref90 full databases running _humann\_databases --download chocophlan full $INSTALL\_LOCATION_ and _humann\_databases --download uniref uniref90\_diamond $INSTALL\_LOCATION_ respectively. I have paired-end data, and converted it to a single file through cat.  
when I ran _humann --input SLG\_cat.fastq --output humann3\_output_ I am getting an error message **CRITICAL ERROR: The directory provided for ChocoPhlAn contains files ( full\_chocophlan.v296\_201901.tar.gz ) that are not of the expected version. Please install the latest version of the database: 201901b**.

I followed this link [Difficulty downloading databases in humann3 - #24 by sagunmaharjann](https://forum.biobakery.org/t/difficulty-downloading-databases-in-humann3/1343/24) and downloaded full\_chocophlan.v296\_201901b.tar.gz and configured the path. when I reran _humann --input SLG\_cat.fastq --output humann3\_output_ I got another error **CRITICAL ERROR: The directory provided for ChocoPhlAn does not contain files of the expected format (ie ‘^[g\_\_][s\_\_]’).**  
I am unable to detect where I’m doing wrong.  
Pls help me out.

 ![Screenshot from 2021-08-07 16-23-28](https://canada1.discourse-cdn.com/flex027/uploads/biobakery/original/1X/a3fe3407e1a2cc06c9a1de1597f1e141a3d3dec7.png)

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**Author:** ![franzosa](https://yyz1.discourse-cdn.com/flex027/user_avatar/forum.biobakery.org/franzosa/32/3511_2.png) [@franzosa](https://forum.biobakery.org/u/franzosa)\
**Post date:** [August 10, 2021, 4:32pm UTC](https://forum.biobakery.org/t/downlodaing-uniref90-full-database/2464/4 "2021-08-10T16:32:37Z")

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It looks like you have the original zipped archive (full\_chocophlan.v296\_201901.tar.gz) in the folder with the unzipped contents. HUMAnN is complaining because that file doesn’t look like a pangenome. If you move that file out of the unzipped pangenomes folder it should solve this problem.

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**Author:** ![Ivy](https://avatars.discourse-cdn.com/v4/letter/i/bc8723/32.png) [@Ivy](https://forum.biobakery.org/u/Ivy)\
**Post date:** [August 14, 2021, 2:23pm UTC](https://forum.biobakery.org/t/downlodaing-uniref90-full-database/2464/5 "2021-08-14T14:23:59Z")

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Thanks Eric, It works!
