# DIAMOND version in HUMANN

**URL:** <https://forum.biobakery.org/t/diamond-version-in-humann/3319>\
**Category:** HUMAnN\
**Created:** [March 15, 2022, 10:10pm UTC](https://forum.biobakery.org/t/diamond-version-in-humann/3319 "2022-03-15T22:10:00Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![jorondo1](https://yyz1.discourse-cdn.com/flex027/user_avatar/forum.biobakery.org/jorondo1/32/1312_2.png) [@jorondo1](https://forum.biobakery.org/u/jorondo1)\
**Post date:** [March 15, 2022, 10:10pm UTC](https://forum.biobakery.org/t/diamond-version-in-humann/3319/1 "2022-03-15T22:10:00Z")

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We are using DIAMOND 2.0.14 in our humann pipeline and we are wondering if it’s a good idea since humann seems to have been configured for the 0.9 version. Has it been tested? Can we pass some of the new options ?

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**Author:** ![franzosa](https://yyz1.discourse-cdn.com/flex027/user_avatar/forum.biobakery.org/franzosa/32/3511_2.png) [@franzosa](https://forum.biobakery.org/u/franzosa)\
**Post date:** [March 25, 2022, 3:51pm UTC](https://forum.biobakery.org/t/diamond-version-in-humann/3319/2 "2022-03-25T15:51:26Z")

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We have not tested DIAMOND 2.0 within HUMAnN yet. I suspect it will work fine and provide some nice improvements. 🙂 If you’d like to experiment, you could potentially try running it in the context of the HUMAnN 3 tutorial to see if it produces similar outputs:

> **[humann3 · biobakery/biobakery Wiki](https://github.com/biobakery/biobakery/wiki/humann3)**
>
> bioBakery tools for meta'omic profiling. Contribute to biobakery/biobakery development by creating an account on GitHub.

That said, I’m not sure if DIAMOND 2.0 can work with the DIAMOND 0.9.36-formatted databases we bundle with HUMAnN 3 (the database format has changed a few times during development).

In HUMAnN 3 you can pass additional options to the DIAMOND binary via the `--diamond-options` flag (this should work across DIAMOND versions).